Nanoparticle Treatment Could Help Reduce Disability from Blast Injury

Explosions on the battlefield can cause significant internal damage. Organs such as the lungs are susceptible to injuries that may not be readily apparent, and by the time the wounds are discovered, it may be too late to save the soldier’s life. With this in mind, researchers developed a new treatment method to repair damage in rats using nanoparticles and are now seeking to develop the treatment for human use.

The research study, published in the ACS Macro Letters journal, was funded by the U.S. Department of Defense (DoD) in hopes that it could be a faster treatment on the battlefield. Doctors drew on past research to develop a type of nanoparticle that promoted clot-formation and carried an anti-inflammatory corticosteroid. These two therapies helped stop the internal bleeding and cellular damage in the lungs of rats after traumatic injury.

Much like soldiers in the proximity of an explosive device, rats also suffer small internal lesions on their lungs due to the force of the blast. The internal bleeding is often undetected until it is too late and is difficult to treat outside of a hospital. The nanoparticle treatment is more easily administered in the field and can improve oxygen intake and reduce bleeding within 10 minutes of injection. The researchers hope this new therapy will help reduce the number of active duty deaths and long-term damage by offering more immediate treatment.

Even being in the proximity of an explosion can cause head trauma, internal bleeding, and other injuries. When treatment is delayed, these conditions can become permanent disabilities or even lead to death. If you are a veteran who suffered a disabling condition due to an explosion during active duty, you may be eligible for veterans’ disability benefits. For help filing your claim or appealing a decision from the Department of Veterans Affairs, contact Veterans Help Group®. Call today – 1-855-855-8992.